Xpert® BCR-ABL Ultra

Brand : Cepheid
Category : TCM

Xpert® BCR-ABL Ultra - Sensitive and quantitative monitoring of BCR-ABL mRNA in patients with chronic myelogenous leukemia (CML).

Xpert BCR-ABL Ultra is a quantitative test for BCR-ABL major breakpoint (p210) transcripts that provides highly sensitive and on-demand molecular results.

Based on the innovative GeneXpert® technology, Xpert BCR-ABL Ultra automates the entire test process including RNA isolation, reverse transcription, and fully-nested real-time PCR of BCR-ABL target gene and ABL reference gene, in one fully automated cartridge.

Product advantages :

  • Ease of use.
  • <2.5 hours total process.
  • Simply add treated blood sample and an off-board reagent to the Xpert cartridge.
  • Results aligned to the IS lot-to-lot through secondary standards calibrated to the BCR-ABL WHO panel.
  • Sensitive.
  • Includes two internal controls.
  • Only 4 mL input volume of whole blood ensures reproducible detection of low-level transcripts.
  • High sensitivity and low inter-laboratory variation.
  • Clinically demonstrated limit of detection of <4.5-log reduction (0.0030%).

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